WebKenmotsu H, Yamamoto N, Yamanaka T, et al. Randomized Phase III study of pemetrexed plus cisplatin versus vinorelbine plus cisplatin for completely resected Stage II to IIIA non-squamous non-small cell lung cancer. J Clin Oncol. 2024; 38(19): 2187 -2196 2. Ciuleanu T, Brodowicz T, Zielinski C, et al. Maintenance pemetrexed plus best supportive care WebThe most common adverse reactions (incidence ≥20%) with single-agent use are fatigue, nausea, and anorexia. Additional common adverse reactions when used in combination with cisplatin include...
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WebMar 27, 2024 · Regimens recommended by NCCN include pemetrexed plus cisplatin with or without bevacizumab and nivolumab plus ipilimumab. However, regimens in subsequent lines remain controversial. In the past decades, physicians have conducted clinical trials to assess and compare different chemotherapy drugs, including gemcitabine, vinorelbine, … WebPurpose: To assess the efficacy of pemetrexed plus platinum doublet chemotherapy as first-line treatment for advanced nonsquamous non-small-cell lung cancer (NSCLC) through a trial-level meta-analysis. Methods: Trials published between 1990 and 2015 were identified by an electronic search of public databases (Medline, Embase, and Cochrane Library). iphone rtt/tty
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WebDec 19, 2024 · Pemetrexed 500 mg/m 2 and cisplatin 75 mg/m 2 (non-squamous histology) or Gemcitabine 1000-1250 mg/m 2 and cisplatin 75 mg/m 2 (squamous histology) Patients with comorbidities or patients not... WebDec 14, 2024 · Cisplatin and pemetrexed are currently recognized as the best combination chemotherapy for mesothelioma and some other types of cancer. As a result, cisplatin and pemetrexed are often used as a baseline when evaluating the efficacy of new chemotherapy drugs and other cancer therapies. WebApr 4, 2024 · Patients also received pemetrexed 500 mg/m 2 plus cisplatin 75 mg/m 2 or carboplatin area under the curve 5 mg/mL/min once every 3 weeks for four cycles … orange county to paine field flights