NettetWe demonstrated that the assay has a high density of diagnostic SNPs for backcrossing the BALB/c strain into the C57BL/6J strain (807–819 SNPs), and a sufficient density of diagnostic SNPs for ... NettetBackcross breeding enables breeders to transfer a desired trait such as a transgene from one variety (donor parent, DP) into the favored genetic background of another (recurrent parent, RP). If the trait of interest is produced by a dominant gene, this process involves four rounds of backcrossing wi …
Transgenic and Knockout Core - CRISPR/Cas9 Targeting
NettetNational Center for Biotechnology Information Nettet19. jan. 2016 · The N1F1 mice are backcrossed to the B6 mice and the resulting N2F1 mice are partly B6 like on the chromosome carrying the mutation of interest, but the block around the mutation of interest remains 129-like. With each generation of backcrossing, the 129-like region gets smaller around the mutation of interest, but is never completely … is bear healthy
Genes Free Full-Text Fine Mapping of the Mouse Ath28 Locus …
NettetBackcrossing is a two-generation breeding protocol that starts by generating hybrid F1 mice between two inbred strains (preferably distantly related), one of them carrying the … Nettet7. des. 2016 · Because ovulation can be induced in female mice as early as 3 weeks of age, superovulation-aided backcrossing of marker-selected females could … NettetCross mice to a genetically controlled inbred strain. At commercial suppliers or in controlled breeding colonies, inbred mice are rederived from archived stock every five to ten generations, greatly reducing genetic drift and inbreeding depression. Backcrossing the GA strain to a genetically controlled inbred strain should reinvigorate the ... is bearing clockwise