WebJul 22, 2016 · Saccharothriolide F (3) was identified to be a demethylated congener of saccharothriolides D (1) and A (4) at the C-2 position. The availability of compounds 1-6 enabled a structure-activity relationship study that revealed the importance of the phenolic hydroxy group at C-2″ and the stereochemistry of C-2 for the inhibition of human ... WebTwo novel macrolactams, dracolactams A and B, were identified from a combined-culture of Micromonospora species and a mycolic-acid containing bacterium (MACB). Their structures and stereochemistries were completely assigned, based on spectroscopic analyses and chemical derivatization. Both dracolactams were probably generated from a …

Enhancement of saccharothriolide production and discovery of a …

WebSaccharothriolides A-C, novel phenyl-substituted 10-membered macrolides from a rare actinomyceteSaccharothrixsp. Shan Lu,aShinichi Nishimura,aGo Hirai,b Masashi Ito,c Teppei Kawahara,dMiho Izumikawa,d Mikiko Sodeoka,b Kazuo Shin … WebSaccharothriolide B C25H31NO7 CID 134151810 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... jill biden reveals christmas decorations

Macrolides from rare actinomycetes: Structures and bioactivities

WebApr 1, 2015 · Saccharothriolide A ( 1) was obtained as a light yellow oil with [ α] 20 D + 18.0 ( c = 0.74, MeOH). The molecular formula was determined to be C 26 H 31 NO 8 by HR-ESI … WebSaccharothriolide A C26H31NO8 CID 139585834 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … Websaccharothriolide A (1), exhibited an MS signal (m/z 486.2134 [M + H]+) which was not found in metabolites database and a UV absorption at 345 nm characteristic to … installing pavers on sloped ground